Write the name of disorders caused due to hypo and hyper secretion of adrenal corticoids. Mention any 3 symptoms of each of these disorders.

Answer:

Hyposecretion — Addison’s disease. Symptoms (any three):

1. Low blood pressure (hypotension) and low blood sugar (hypoglycaemia).
2. Muscular weakness and fatigue, loss of weight.
3. Bronze-like pigmentation of the skin.
4. Loss of Na⁺ and water in urine, dehydration; nausea and vomiting.

Hypersecretion — Cushing’s syndrome (excess cortisol). Symptoms (any three):

1. Obesity of face (moon face) and trunk, with fat deposit on the back (buffalo hump).
2. High blood sugar (hyperglycaemia) and high blood pressure due to Na⁺ and water retention.
3. Muscle weakness, thinning of skin with purple stretch marks; osteoporosis.

(Hypersecretion of aldosterone causes Conn’s syndrome / aldosteronism, with hypertension and muscle weakness.)