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  1. Prevention of waste: It is better to prevent the formation of waste than to treat or clean it up after it is formed.
  2. Atom economy: Synthetic methods should be designed so that the maximum number of atoms of the reactants are incorporated into the final product.
  3. Safer solvents and auxiliaries: Use of hazardous solvents and other auxiliary substances should be avoided; safer solvents such as water should be used.
  4. Use of catalysts: Catalytic reagents, which are selective and are not consumed, are better than stoichiometric reagents.
Doubtly AI · 29 Oct 2026 AI-verified · Nov 2026 Report
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