Topic: Skeletal system, joints and disorders· Human Physiology

Osteoporosis, an age-related disease of skeletal system, may occur due to

1. high concentration of Ca\(^{++}\) and Na\(^{+}\)

2. decreased level of estrogen

3. accumulation of uric acid leading to inflammation of joints

4. immune disorder affecting neuro-muscular junction leading to fatigue

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Answer: 2. decreased level of estrogen

Osteoporosis is a loss of bone mass that makes bones fragile. It is common after menopause or in old age because the level of estrogen falls, and estrogen helps keep bone deposition going.

Option 3 describes gout, and option 4 describes myasthenia gravis. High Ca⁺⁺ and Na⁺ does not cause osteoporosis.

Doubtly AI · 30 Oct 2026 AI-generated · not yet verified Report

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Osteoporosis, an age-related disease of skeletal system, may occur due to

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