1. G ₂ /M 2. M 3. Both G ₂ /M and M 4. G ₁ /S

Topic: Cell cycle, mitosis, meiosis· Cell Structure and Function

When cell has stalled DNA replication fork, which checkpoint should be predominantly activated?

1. G\(_2\)/M

2. M

3. Both G\(_2\)/M and M

4. G\(_1\)/S

Doubtly Asked 30 Oct 2026 NEET UG 2016 Phase 2 Practice test neet Save WhatsApp Report

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Answer: 1. G\(_2\)/M

A stalled replication fork means DNA is not fully replicated. The cell must delay entry into mitosis until replication and repair are complete. This is done by the G₂/M checkpoint, which checks that DNA is fully replicated and undamaged before mitosis.

The G₁/S checkpoint checks DNA before replication begins. The M (spindle) checkpoint checks chromosome attachment.

Doubtly AI · 30 Oct 2026 AI-generated · not yet verified Report

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When cell has stalled DNA replication fork, which checkpoint should be predominantly activated?

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