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Answer: (d) Pleiotropy

In pleiotropy a single gene affects several traits. In sickle-cell anaemia the gene HbS is lethal in the homozygous condition (HbSHbS individuals die), so a cross between two carriers (HbAHbS) gives normal (HbAHbA) and carrier (HbAHbS) survivors in the ratio 1 : 2 instead of 3 : 1. (Incomplete dominance and codominance modify 3 : 1 to 1 : 2 : 1.)

Doubtly AI · 29 Oct 2026 AI-verified · Nov 2026 Report
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