Topic: Sex-linked inheritance, Mendelian and chromosomal disorders· Genetics and Evolution

A disease caused by an autosomal primary non-disjunction is :

1. Klinefelter's Syndrome

2. Turner's Syndrome

3. Sickle Cell Anemia

4. Down's Syndrome

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Answer: 4. Down's Syndrome

Key idea: Non-disjunction of an autosome gives a trisomy or monosomy of an autosome.

Down's syndrome is trisomy 21, an autosome. Klinefelter's (XXY) and Turner's (XO) result from sex chromosome non-disjunction, and sickle cell anaemia is a single gene (point mutation) disorder. Answer: (4).

Doubtly AI · 30 Oct 2026 AI-generated · not yet verified Report

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A disease caused by an autosomal primary non-disjunction is :

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