Sex-linked inheritance, Mendelian and chromosomal disorders
Top questions
See all →- With the help of given pedigree, find out the probability for the birth of a child having no disease and being a carrier (has the disease mutation in one allele of the gene) in F3 generation. Answer: 1. 1/4 Key idea: The legend shows carriers only among females, so the trait is X-linked recessive. The F2 mother is a carrier: X^AX^... 1
- Match List I with List II :List I:A. Down's syndromeB. α-ThalassemiaC. β-ThalassemiaD. Klinefelter's syndromeList II:I. 11^th chromosomeII. 'X' chromosomeIII. 21^st chromosomeIV. 16^th chromosomeChoose the correct answer from the options given below… Answer: 4. A-III, B-IV, C-I, D-II Down's syndrome - trisomy of chromosome 21 (A-III). α-Thalassemia - chromosome 16 (B-IV). β-Thalassemia -... 1
- Broad palm with single palm crease is visible in a person suffering from- Answer: 2. Down's syndrome Key idea: Down's syndrome (trisomy 21) has typical physical features. These include a short stature, a small roun... 1
- Which one of the following symbols represents mating between relatives in human pedigree analysis? Answer: 3. [pedigree symbol: square joined to circle by double line] Key idea: In a human pedigree, a double horizontal line between the mal... 1
- Which of the following statements are correct about Klinefelter's Syndrome?A. This disorder was first described by Langdon Down (1866).B. Such an individual has overall masculine development. However, the feminine development is also expressed.C. The… Answer: 4. B and E only Key idea: Klinefelter's syndrome has the karyotype 47, XXY. A is wrong: Langdon Down described Down syndrome. B is c... 1
- If a colour blind female marries a man whose mother was also colour blind, what are the chances of her progeny having colour blindness ? Answer: 1. 100% Key idea: Colour blindness is X-linked recessive. The female is colour blind: X^cX^c . The man's mother was colour blind, so... 1