Topic: Sex-linked inheritance, Mendelian and chromosomal disorders· Genetics and Evolution

In a cross between a male and female, both heterozygous for sickle cell anaemia gene, what percentage of the progeny will be diseased ?

1. 50%

2. 75%

3. 25%

4. 100%

Doubtly Asked 30 Oct 2026 NEET UG 2021 Practice test neet Save WhatsApp Report

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Answer: 3. 25%

Both parents are heterozygous carriers (Hb\(^A\)Hb\(^S\)). Cross: Hb\(^A\)Hb\(^S\) × Hb\(^A\)Hb\(^S\) gives 1 Hb\(^A\)Hb\(^A\) : 2 Hb\(^A\)Hb\(^S\) : 1 Hb\(^S\)Hb\(^S\).

Only Hb\(^S\)Hb\(^S\) is diseased, i.e. 1/4 = 25%.

Doubtly AI · 30 Oct 2026 AI-generated · not yet verified Report

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In a cross between a male and female, both heterozygous for sickle cell anaemia gene, what percentage of the progeny will be diseased ?

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