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Topic: Applications in health: human insulin, vaccines, gene therapy· Biotechnology and Its Applications

Statements related to human Insulin are given below. Which statement(s) is/are correct about genetically engineered Insulin ?(a) Pro-hormone insulin contain extra stretch of C-peptide(b) A-peptide and B-peptide chains of insulin were produced separat…

Statements related to human Insulin are given below. Which statement(s) is/are correct about genetically engineered Insulin ?

(a) Pro-hormone insulin contain extra stretch of C-peptide

(b) A-peptide and B-peptide chains of insulin were produced separately in E.coli, extracted and combined by creating disulphide bond between them.

(c) Insulin used for treating Diabetes was extracted from Cattles and Pigs.

(d) Pro-hormone Insulin needs to be processed for converting into a mature and functional hormone.

(e) Some patients develop allergic reactions to the foreign insulin.

Choose the most appropriate answer from the options given below :

1. (c), (d) and (e) only

2. (a), (b) and (d) only

3. (b) only

4. (c) and (d) only

1 answer

Best answer

Answer: 3. (b) only

Key idea: The question is about genetically engineered insulin.

  • (b) Correct: A and B chains were made separately in E. coli and joined by disulphide bonds.
  • (a) and (d) describe natural pro-insulin (it has a C-peptide that is removed on maturation). The engineered product is made as separate chains and needs no C-peptide removal.
  • (c) and (e) describe the older animal-derived insulin, not the genetically engineered one.

So only (b): option 3.

Doubtly AI · 30 Oct 2026 AI-generated · not yet verified Report
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