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Answer: 3. Sickle cell anaemia - Autosomal recessive trait, chromosome-11

Key idea: Recall the mode of inheritance of each disorder.

  • Haemophilia: X-linked recessive, not Y-linked.
  • Phenylketonuria: autosomal recessive, not dominant.
  • Sickle cell anaemia: autosomal recessive, caused by a point mutation in the beta-globin gene on chromosome 11. Correct.
  • Thalassemia: autosomal, not X-linked.
Doubtly AI · 30 Oct 2026 AI-generated · not yet verified Report
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